abstract：OBJECTIVE:To test the hypothesis that radiography of the lumbar spine in patients with low back pain is not associated with improved clinical outcomes or satisfaction with care. DESIGN:Randomised unblinded controlled trial. SETTING:73 general practices in Nottingham, north Nottinghamshire, southern Derbyshire, north ...

journal_title：BMJ (Clinical research ed.)

authors： Kendrick D,Fielding K,Bentley E,Kerslake R,Miller P,Pringle M

更新日期：2001-02-17 00:00:00

abstract：OBJECTIVE:To determine whether abnormal results for liver function tests are investigated in primary care and findings on full investigation. DESIGN:Retrospective audit and prospective clinical investigation. SETTING:University hospital and surrounding general practices serving around 330 000 people. SUBJECTS:Adults...

journal_title：BMJ (Clinical research ed.)

authors： Sherwood P,Lyburn I,Brown S,Ryder S

更新日期：2001-02-03 00:00:00

abstract：OBJECTIVE:To investigate whether an important football match increases stress to such an extent that it triggers acute myocardial infarction and stroke. DESIGN:Longitudinal study of mortality around 22 June 1996 (the day the Dutch football team was eliminated from the European football championship). Mortality on 22 J...

journal_title：BMJ (Clinical research ed.)

authors： Witte DR,Bots ML,Hoes AW,Grobbee DE

更新日期：2000-12-23 00:00:00

abstract：OBJECTIVE:To develop an evidence base for recommendations on the use of atypical antipsychotics for patients with schizophrenia. DESIGN:Systematic overview and meta-regression analyses of randomised controlled trials, as a basis for formal development of guidelines. SUBJECTS:12 649 patients in 52 randomised trials co...

journal_title：BMJ (Clinical research ed.)

authors： Geddes J,Freemantle N,Harrison P,Bebbington P

更新日期：2000-12-02 00:00:00

abstract：OBJECTIVES:To compare "hospital at home" and hospital care as an inpatient in acute exacerbations of chronic obstructive pulmonary disease. DESIGN:Prospective randomised controlled trial with three months' follow up. SETTING:University teaching hospital offering secondary care service to 350 000 patients. PATIENTS:S...

journal_title：BMJ (Clinical research ed.)

authors： Davies L,Wilkinson M,Bonner S,Calverley PM,Angus RM

更新日期：2000-11-18 00:00:00

abstract：OBJECTIVE:To evaluate the effect of intensive geriatric rehabilitation on demented patients with hip fracture. DESIGN:Preplanned subanalysis of randomised intervention study. Settting: Jyväskylä Central Hospital, Finland. PARTICIPANTS:243 independently living patients aged 65 years or older admitted to hospital with ...

journal_title：BMJ (Clinical research ed.)

authors： Huusko TM,Karppi P,Avikainen V,Kautiainen H,Sulkava R

更新日期：2000-11-04 00:00:00

abstract：OBJECTIVES:To calculate socioeconomic and health status measures for the primary care groups in London and to examine the association between these measures and hospital admission rates. DESIGN:Cross sectional study. SETTING:66 primary care groups in London, total list size 8.0 million people. MAIN OUTCOME MEASURES:...

journal_title：BMJ (Clinical research ed.)

authors： Majeed A,Bardsley M,Morgan D,O'Sullivan C,Bindman AB

更新日期：2000-10-28 00:00:00

abstract：OBJECTIVE:To evaluate the primary care communications initiative, which introduced NHSnet to primary care in Scotland. DESIGN:Semi-structured telephone interviews, postal questionnaire. SETTING:All 15 Scottish health boards, random sample of 1 in 3 of all Scottish general practices. PARTICIPANTS:Information manageme...

journal_title：BMJ (Clinical research ed.)

authors： Willmot M,Sullivan F

更新日期：2000-10-07 00:00:00

abstract：OBJECTIVES:To assess heat related mortalities in relation to climate within Europe. DESIGN:Observational population study. SETTING:North Finland, south Finland, Baden-Württemberg, Netherlands, London, north Italy, and Athens. SUBJECTS:People aged 65-74. MAIN OUTCOME MEASURES:Mortalities at temperatures above, below...

journal_title：BMJ (Clinical research ed.)

authors： Keatinge WR,Donaldson GC,Cordioli E,Martinelli M,Kunst AE,Mackenbach JP,Nayha S,Vuori I

更新日期：2000-09-16 00:00:00

abstract：:In the existing WHO guidelines, complementary feeding at 4-6 months is advocated. However, many nutrition specialists believe that these guidelines lead to complementary foods being offered from the age of 3 months, or even earlier, subsequently suggesting that the WHO should change its recommendations to about 6 mon...

journal_title：BMJ (Clinical research ed.)

authors： Yamey G

更新日期：2000-09-09 00:00:00

abstract：OBJECTIVES:To examine the influence of parental age at delivery and birth order on subsequent risk of childhood diabetes. DESIGN:Prospective population based family study. SETTING:Area formerly administered by the Oxford Regional Health Authority. PARTICIPANTS:1375 families in which one child or more had diabetes. O...

journal_title：BMJ (Clinical research ed.)

authors： Bingley PJ,Douek IF,Rogers CA,Gale EA

更新日期：2000-08-12 00:00:00

abstract：OBJECTIVE:To compare the risk profile of women receiving public and private obstetric care and to compare the rates of obstetric intervention among women at low risk in these groups. DESIGN:Population based descriptive study. SETTING:New South Wales, Australia. SUBJECTS:All 171,157 women having a live baby during 19...

journal_title：BMJ (Clinical research ed.)

authors： Roberts CL,Tracy S,Peat B

更新日期：2000-07-15 00:00:00

abstract：OBJECTIVE:To estimate trends between 1972-6 and 1996 in the prevalences of asthma and hay fever in adults. DESIGN:Two epidemiological surveys 20 years apart. Identical questions were asked about asthma, hay fever, and respiratory symptoms at each survey. SETTING:Renfrew and Paisley, two towns in the west of Scotland....

journal_title：BMJ (Clinical research ed.)

authors： Upton MN,McConnachie A,McSharry C,Hart CL,Smith GD,Gillis CR,Watt GC

更新日期：2000-07-08 00:00:00

abstract：OBJECTIVE:To estimate the association between maternal age and fetal death (spontaneous abortion, ectopic pregnancy, stillbirth), taking into account a woman's reproductive history. DESIGN:Prospective register linkage study. SUBJECTS:All women with a reproductive outcome (live birth, stillbirth, spontaneous abortion ...

journal_title：BMJ (Clinical research ed.)

authors： Nybo Andersen AM,Wohlfahrt J,Christens P,Olsen J,Melbye M

更新日期：2000-06-24 00:00:00

abstract：OBJECTIVE:To assess whether a raised serum troponin T concentration would be an independent predictor of death in patients with an acute ischaemic stroke. DESIGN:Observational study. SETTING:Auckland Hospital, Auckland, New Zealand. SUBJECTS:All 181 patients with an acute ischaemic stroke admitted over nine months i...

journal_title：BMJ (Clinical research ed.)

authors： James P,Ellis CJ,Whitlock RM,McNeil AR,Henley J,Anderson NE

更新日期：2000-06-03 00:00:00

abstract：:The UN has reported that five multinational pharmaceutical companies would cut down HIV drug prices in the developing world. One of these drug companies is GlaxoWellcome, which has promised to reduce the price of zidovudine and lamivudine to US$2 in the poorest nations, a fifth of its price in the US. Although Peter ...

journal_title：BMJ (Clinical research ed.)

authors： Yamey G

更新日期：2000-05-20 00:00:00

abstract：OBJECTIVE:To investigate the impact of patients' preferences for the treatment of atrial fibrillation, by using individualised decision analysis combining probability and utility assessments into a decision tree. DESIGN:Observational study based on interviews with patients. SETTING:Eight general practices in Avon. P...

journal_title：BMJ (Clinical research ed.)

authors： Protheroe J,Fahey T,Montgomery AA,Peters TJ

更新日期：2000-05-20 00:00:00

abstract：OBJECTIVES:To study prospectively the differences in health inequality in men and women from 1986-96 using the Office for National Statistics' longitudinal study and new socioeconomic classification. To assess the relative importance of social class (based on employment characteristics) and social position according to...

journal_title：BMJ (Clinical research ed.)

authors： Sacker A,Firth D,Fitzpatrick R,Lynch K,Bartley M

更新日期：2000-05-13 00:00:00

abstract：OBJECTIVE:To determine the risk factors for neonatal encephalopathy among term infants in a developing country. DESIGN:Unmatched case-control study. SETTING:Principal maternity hospital of Kathmandu, Nepal. SUBJECTS:All 131 infants with neonatal encephalopathy from a population of 21 609 infants born over an 18 mont...

journal_title：BMJ (Clinical research ed.)

authors： Ellis M,Manandhar N,Manandhar DS,Costello AM

更新日期：2000-05-06 00:00:00

abstract：OBJECTIVE:To investigate the facilities for inpatient care of mentally disordered people in prison. DESIGN:Semistructured inspections conducted by doctor and nurse. Expected standards were based on healthcare quality standards published by the Prison Service or the NHS. SETTING:13 prisons with inpatient beds in Engla...

journal_title：BMJ (Clinical research ed.)

authors： Reed JL,Lyne M

更新日期：2000-04-15 00:00:00

abstract：OBJECTIVES:To explore why cancer patients do not want or seek information about their condition beyond that volunteered by their physicians at times during their illness. DESIGN:Qualitative study based on in-depth interviews. SETTING:Outpatient oncology clinics at a London cancer centre. PARTICIPANTS:17 patients wit...

journal_title：BMJ (Clinical research ed.)

authors： Leydon GM,Boulton M,Moynihan C,Jones A,Mossman J,Boudioni M,McPherson K

更新日期：2000-04-01 00:00:00

abstract：OBJECTIVE:To examine variations in teenage pregnancy rates in Trent region and to determine possible associations with local general practice characteristics such as the age and sex of the doctors. DESIGN:Cross sectional survey. SETTING:All 826 general practices in Trent region in existence between 1994 and 1997. SU...

journal_title：BMJ (Clinical research ed.)

authors： Hippisley-Cox J,Allen J,Pringle M,Ebdon D,McPhearson M,Churchill D,Bradley S

更新日期：2000-03-25 00:00:00

abstract：OBJECTIVE:To assess the effects of preventive home visits to elderly people living in the community. DESIGN:Systematic review. SETTING:15 trials retrieved from Medline, Embase, and the Cochrane controlled trial register. MAIN OUTCOME MEASURES:Physical function, psychosocial function, falls, admissions to institution...

journal_title：BMJ (Clinical research ed.)

authors： van Haastregt JC,Diederiks JP,van Rossum E,de Witte LP,Crebolder HF

更新日期：2000-03-18 00:00:00

abstract：OBJECTIVE:To evaluate whether follow up of patients with inflammatory bowel disease is better through open access than by routine booked appointments. DESIGN:Pragmatic randomised controlled trial. SETTING:Two district general hospitals in Swansea and Neath, Wales. PARTICIPANTS:180 adults (78 with Crohn's disease, 77...

journal_title：BMJ (Clinical research ed.)

authors： Williams JG,Cheung WY,Russell IT,Cohen DR,Longo M,Lervy B

更新日期：2000-02-26 00:00:00

abstract：OBJECTIVE:To assess whether sleep apnoea syndrome is an independent risk factor for hypertension. DESIGN:Population study. SETTING:Sleep clinic in Toronto. PARTICIPANTS:2,677 adults, aged 20-85 years, referred to the sleep clinic with suspected sleep apnoea syndrome. OUTCOME MEASURES:Medical history, demographic da...

journal_title：BMJ (Clinical research ed.)

authors： Lavie P,Herer P,Hoffstein V

更新日期：2000-02-19 00:00:00

abstract：:South African Health Minister Dr. Manto Tshabalala-Msimang was accused of human rights abuse for refusing to supply zidovudine to all HIV-positive pregnant women. The accusations were laid by Dr. Costa Gazi, a South African doctor employed in the state health system with the Human Rights Commission. Dr. Gazi believe...

journal_title：BMJ (Clinical research ed.)

authors： Sidley P

更新日期：2000-01-29 00:00:00

abstract：OBJECTIVE:To evaluate the cost utility of interferon beta-1b in secondary progressive multiple sclerosis. DESIGN:Population based cost utility model (healthcare perspective). Data on use of health services were obtained from case records and routine morbidity data and utility values from a EuroQol survey. Local and pu...

journal_title：BMJ (Clinical research ed.)

authors： Forbes RB,Lees A,Waugh N,Swingler RJ

更新日期：1999-12-11 00:00:00

abstract：OBJECTIVES:To compare the costs of admission to a hospital at home scheme with those of acute hospital admission. DESIGN:Cost minimisation analysis within a pragmatic randomised controlled trial. SETTING:Hospital at home scheme in Leicester and the city's three acute hospitals. PARTICIPANTS:199 consecutive patients ...

journal_title：BMJ (Clinical research ed.)

authors： Jones J,Wilson A,Parker H,Wynn A,Jagger C,Spiers N,Parker G

更新日期：1999-12-11 00:00:00

abstract：:The rapid aging of populations in developing countries as compared to those in the developed world has implications for medical training in these places. Moreover, the growing globalization of employment for many health professionals means that demographic shifts have implications for the training of health professio...

journal_title：BMJ (Clinical research ed.)

authors： Ebrahim S

更新日期：1999-11-20 00:00:00

abstract：OBJECTIVE:To compare the use and effect of a computer based information system for cancer patients that is personalised using each patient's medical record with a system providing only general information and with information provided in booklets. DESIGN:Randomised trial with three groups. Data collected at start of r...

journal_title：BMJ (Clinical research ed.)

authors： Jones R,Pearson J,McGregor S,Cawsey AJ,Barrett A,Craig N,Atkinson JM,Gilmour WH,McEwen J

更新日期：1999-11-06 00:00:00

abstract：:This article reports the success of WHO in eliminating onchocerciasis or river blindness in most of West Africa. The onchocerciasis control program was able to save 100,000 people at immediate risk of contracting the disease and prevented the infection of about 12 million children. About 1.25 million onchocercal inf...

journal_title：BMJ (Clinical research ed.)

authors： Ciment J

更新日期：1999-10-23 00:00:00

abstract：:This paper examines the impact of marital status on maternal mortality in the period before and the period after German reunification in the area covered by the former East Germany. Maternal mortality ratio prior to the reunification was stable and declined after reunification. This can be attributed to the adoption ...

journal_title：BMJ (Clinical research ed.)

authors： Razum O,Jahn A,Snow R

更新日期：1999-10-23 00:00:00

abstract：OBJECTIVE:To compare the clinical effectiveness of local corticosteroid injection, standard non-steroidal anti-inflammatory drugs, and simple analgesics for the early treatment of lateral epicondylitis in primary care. DESIGN:Multicentre pragmatic randomised controlled trial. SETTING:23 general practices in North Sta...

journal_title：BMJ (Clinical research ed.)

authors： Hay EM,Paterson SM,Lewis M,Hosie G,Croft P

更新日期：1999-10-09 00:00:00

abstract：OBJECTIVE:To study the effects on children of humanitarian aid agencies restricting help to refugee families (internally displaced people). DESIGN:Follow up study of 3 months. SETTING:Prabis peninsular outside Bissau, the capital of Guinea-Bissau, which has functioned as a refugee area for internally displaced people...

journal_title：BMJ (Clinical research ed.)

authors： Aaby P,Gomes J,Fernandes M,Djana Q,Lisse I,Jensen H

更新日期：1999-10-02 00:00:00

abstract：OBJECTIVES:To identify the need for reproductive health care among a community affected by conflict, and to ascertain the priority given by the community to reproductive health issues. DESIGN:Rapid appraisal. This comprised interviews with key informants, in-depth interviews, and group discussions. Secondary data were...

journal_title：BMJ (Clinical research ed.)

authors： Palmer CA

更新日期：1999-09-18 00:00:00

abstract：OBJECTIVE:To assess the impact of construction of microdams on the incidence of malaria in nearby communities in terms of possibly increasing peak incidence and prolonging transmission. DESIGN:Four quarterly cycles of malaria incidence surveys, each taking 30 days, undertaken in eight at risk communities close to dams...

journal_title：BMJ (Clinical research ed.)

authors： Ghebreyesus TA,Haile M,Witten KH,Getachew A,Yohannes AM,Yohannes M,Teklehaimanot HD,Lindsay SW,Byass P

更新日期：1999-09-11 00:00:00

abstract：OBJECTIVES:To document the extent to which maternity data are collected and how they are recorded, and to identify problems that may affect their availability throughout the NHS. METHODS:Postal survey in September 1997 with structured questionnaires. SETTING:207 NHS trusts with maternity units in England. PARTICIPAN...

journal_title：BMJ (Clinical research ed.)

authors： Kenney N,Macfarlane A

更新日期：1999-09-04 00:00:00

abstract：AIM:To compare perinatal morbidity and mortality for babies delivered in water with rates for babies delivered conventionally (not in water). DESIGN:Surveillance study (of all consultant paediatricians) and postal survey (of all NHS maternity units). SETTING:British Isles (surveillance study); England and Wales (post...

journal_title：BMJ (Clinical research ed.)

authors： Gilbert RE,Tookey PA

更新日期：1999-08-21 00:00:00

abstract：OBJECTIVE:To determine the implications of variation in mortality associated with use of weapons in different contexts. DESIGN:Literature review. SETTINGS:Armed conflicts and civilian mass shootings, 1929-96. MAIN OUTCOME MEASURE:Mortality from wounds. RESULTS:During the fighting of war the number of people wounded...

journal_title：BMJ (Clinical research ed.)

authors： Coupland RM,Meddings DR

更新日期：1999-08-14 00:00:00

abstract：OBJECTIVE:To investigate the relations of maternal diet and smoking during pregnancy to placental and birth weights at term. DESIGN:Prospective cohort study. SETTING:District general hospital in the south of England. PARTICIPANTS:693 pregnant nulliparous white women with singleton pregnancies who were selected from ...

journal_title：BMJ (Clinical research ed.)

authors： Mathews F,Yudkin P,Neil A

更新日期：1999-08-07 00:00:00